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ea0032p972 | Steroid metabolism and action | ECE2013

Differences in adipose tissue lipolysis in critically ill septic patients with and without shock

Vassiliadi Dimitra , Ilias Ioannis , Kopterides Petros , Nikitas Nikitas , Theodorakopoulou Maria , Diamantakis Argyris , Dimitriadis George , Boutati Eleni , Maratou Irini , Dimopoulou Ioanna

Introduction: Critical illness, and sepsis in particular, drives adipose tissue lipolysis up (with triglycerides (TG) being split to free fatty acids (FFA) and glycerol (GLYC)) to meet increased energy demands. Few studies have addressed lipolysis with tissue microdialysis (MD).Aim: To assess indexes of lipolysis in septic patients with and without shock.Subjects and methods: The study included 110 men and 73 women (mean age+<small...

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ea0026p15 | Adrenal cortex | ECE2011

Interstitial cortisol levels obtained by adipose tissue microdialysis in mechanically ventilated septic patients: correlations with total and free serum cortisol

Ilias I , Dimopoulou I , Nikitas N , Tzanela M , Theodorakopoulou M , Vassiliadi D A , Kopteridis P , Maniatis N , Diamantakis Argyris , Orfanos Stylianos , Perogamvros Ilias , Ungerstedt U , Keevil B G , Tsagarakis Stylianos

Aim: To measure interstitial cortisol obtained by adipose tissue microdialysis (MD) as well as serum total and free cortisol in 31 mechanically ventilated patients upon sepsis onset (days 1 and 2). MD tissue glucose, pyruvate, lactate, and glycerol were also measured (as markers of altered or disrupted local energy production).Methods: The Acute Physiology and Chronic Health Evaluation (APACHE II) on day 1 and the sequential organ failure assessment (SOF...

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Endocrine Abstracts

Differences in adipose tissue lipolysis in critically ill septic patients with and without shock

Interstitial cortisol levels obtained by adipose tissue microdialysis in mechanically ventilated septic patients: correlations with total and free serum cortisol

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